Quantitation of Lipid Peroxidation Product DNA Adducts in Human Prostate by Tandem Mass Spectrometry: A Method That Mitigates Artifacts

Medicine & Life Sciences

• DNA Adducts 100%
• Tandem Mass Spectrometry 87%
• Artifacts 77%
• Lipid Peroxidation 74%
• 1,N2-propano-2'-deoxyguanosine 73%
• Prostate 66%
• Prostatic Neoplasms 38%
• hydroxide ion 36%
• Nucleotides 25%
• Reactive Oxygen Species 25%
• Acrolein 23%
• Deoxyribonucleases 20%
• Inflammation 18%
• Prostatic Hyperplasia 17%
• Preliminary Data 17%
• Liquid Chromatography 16%
• Nucleic Acids 15%
• Digestion 14%
• Mass Spectrometry 14%
• DNA Damage 13%
• Ions 13%
• Poisons 11%
• Oxidative Stress 11%
• Genome 10%
• Lipids 10%
• Mutation 8%
• DNA 8%
• Proteins 5%

Chemical Compounds

• Tandem Mass Spectrometry 66%
• Adduct 56%
• Lipid 55%
• Reactive Oxygen Metabolite 15%
• Nucleotide 13%
• Lipid As 10%
• Acrolein 9%
• Ion Trap 8%
• Oxidative Stress 7%
• Electrospray Ionization 7%
• Mutation 6%
• Nucleic Acid 6%
• Toxic 6%
• Liquid Chromatography 5%
• Mass Spectrometry 5%
• Protein 3%