Relation of neutrophil-to-lymphocyte ratio with GRACE risk score to in-hospital cardiac events in patients with ST-segment elevated myocardial infarction

Ramazan Can Oncel, Mustafa Ucar, Mustafa Serkan Karakas, Baris Akdemir, Atakan Yanikoglu, Ali Riza Gulcan, Refik Emre Altekin, Ibrahim Demir

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

In this study, we aimed to investigate the association of the neutrophil-to-lymphocyte ratio (NLR) with Global Registry of Acute Coronary Events (GRACE) risk score in patients with ST-segment elevated myocardial infarction (STEMI). We analyzed 101 consecutive patients with STEMI. Patients were divided into 3 groups by use of GRACE risk score. The association between NLR and GRACE risk score was assessed. The NLR showed a proportional increase correlated with GRACE risk score (P <.001). The occurrence of in-hospital cardiac death, reinfarction, or new-onset heart failure was significantly related to NLR at admission (P <.001). Likewise, NLR and GRACE risk score showed a significant positive correlation (r =.803, P <.001). In multivariate analysis, NLR resulted as a predictor of worse in-hospital outcomes independent of GRACE risk score. Our study suggests that the NLR is significantly associated with adverse in-hospital outcomes, independent of GRACE risk score in patients with STEMI.

Original languageEnglish (US)
Pages (from-to)383-388
Number of pages6
JournalClinical and Applied Thrombosis/Hemostasis
Volume21
Issue number4
DOIs
StatePublished - May 1 2015

Bibliographical note

Publisher Copyright:
© 2014 The Author(s).

Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.

Keywords

  • GRACE risk score
  • acute myocardial infarction
  • inflammation
  • neutrophil-to-lymphocyte ratio

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