Relation of neutrophil-to-lymphocyte ratio with GRACE risk score to in-hospital cardiac events in patients with ST-segment elevated myocardial infarction

Ramazan Can Oncel; Mustafa Ucar; Mustafa Serkan Karakas; Baris Akdemir; Atakan Yanikoglu; Ali Riza Gulcan; Refik Emre Altekin; Ibrahim Demir

doi:10.1177/1076029613505763

Relation of neutrophil-to-lymphocyte ratio with GRACE risk score to in-hospital cardiac events in patients with ST-segment elevated myocardial infarction

Ramazan Can Oncel, Mustafa Ucar, Mustafa Serkan Karakas, Baris Akdemir, Atakan Yanikoglu, Ali Riza Gulcan, Refik Emre Altekin, Ibrahim Demir

Medicine - Cardiology Division

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33 Scopus citations

Abstract

In this study, we aimed to investigate the association of the neutrophil-to-lymphocyte ratio (NLR) with Global Registry of Acute Coronary Events (GRACE) risk score in patients with ST-segment elevated myocardial infarction (STEMI). We analyzed 101 consecutive patients with STEMI. Patients were divided into 3 groups by use of GRACE risk score. The association between NLR and GRACE risk score was assessed. The NLR showed a proportional increase correlated with GRACE risk score (P <.001). The occurrence of in-hospital cardiac death, reinfarction, or new-onset heart failure was significantly related to NLR at admission (P <.001). Likewise, NLR and GRACE risk score showed a significant positive correlation (r =.803, P <.001). In multivariate analysis, NLR resulted as a predictor of worse in-hospital outcomes independent of GRACE risk score. Our study suggests that the NLR is significantly associated with adverse in-hospital outcomes, independent of GRACE risk score in patients with STEMI.

Original language	English (US)
Pages (from-to)	383-388
Number of pages	6
Journal	Clinical and Applied Thrombosis/Hemostasis
Volume	21
Issue number	4
DOIs	https://doi.org/10.1177/1076029613505763
State	Published - May 1 2015

Bibliographical note

Publisher Copyright:
© 2014 The Author(s).

Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.

Keywords

GRACE risk score
acute myocardial infarction
inflammation
neutrophil-to-lymphocyte ratio

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Oncel, R. C., Ucar, M., Karakas, M. S., Akdemir, B., Yanikoglu, A., Gulcan, A. R., Altekin, R. E., & Demir, I. (2015). Relation of neutrophil-to-lymphocyte ratio with GRACE risk score to in-hospital cardiac events in patients with ST-segment elevated myocardial infarction. Clinical and Applied Thrombosis/Hemostasis, 21(4), 383-388. https://doi.org/10.1177/1076029613505763

Relation of neutrophil-to-lymphocyte ratio with GRACE risk score to in-hospital cardiac events in patients with ST-segment elevated myocardial infarction. / Oncel, Ramazan Can; Ucar, Mustafa; Karakas, Mustafa Serkan et al.
In: Clinical and Applied Thrombosis/Hemostasis, Vol. 21, No. 4, 01.05.2015, p. 383-388.

Research output: Contribution to journal › Article › peer-review

Oncel, RC, Ucar, M, Karakas, MS, Akdemir, B, Yanikoglu, A, Gulcan, AR, Altekin, RE & Demir, I 2015, 'Relation of neutrophil-to-lymphocyte ratio with GRACE risk score to in-hospital cardiac events in patients with ST-segment elevated myocardial infarction', Clinical and Applied Thrombosis/Hemostasis, vol. 21, no. 4, pp. 383-388. https://doi.org/10.1177/1076029613505763

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Relation of neutrophil-to-lymphocyte ratio with GRACE risk score to in-hospital cardiac events in patients with ST-segment elevated myocardial infarction

Abstract

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