Spindle‐cell hemangioendothelioma of the oral cavity. A case report

Konstantinos Tosios, Ioannis G Koutlas, Nikiforos Kapranos, Stavros I. Papanicolaou

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


We describe a vascular tumor classified as SCH by histological criteria that was found in the mandibular‐buccal fold of a 12‐year‐old girl. Microscopically, the lesion consisted of thin‐walled cavernous spaces containing thrombi and phleboliths, and cellular areas composed of spindle‐shaped, epithelioid and vacuolated cells. Immunohistochemically, the endothelial vascular lining was highly reactive with HAM56 antibody, while variable reactivity was observed for factor VIII‐associated antigen. All cell types were positive for vimentin and anti‐PCNA stained less than 3% of the tumor cells. This is the first report of SCH in the oral cavity.

Original languageEnglish (US)
Pages (from-to)379-382
Number of pages4
JournalJournal of Oral Pathology & Medicine
Issue number8
StatePublished - Sep 1995


  • soft tissue tumors
  • spindle cell hemangioendothelioma
  • vascular tumors

Fingerprint Dive into the research topics of 'Spindle‐cell hemangioendothelioma of the oral cavity. A case report'. Together they form a unique fingerprint.

Cite this