TY - JOUR
T1 - Spontaneous Physical Activity Defends Against Obesity
AU - Kotz, Catherine M.
AU - Perez-Leighton, Claudio E.
AU - Teske, Jennifer A.
AU - Billington, Charles J.
PY - 2017/12/1
Y1 - 2017/12/1
N2 - PURPOSE OF REVIEW: Spontaneous physical activity (SPA) is a physical activity not motivated by a rewarding goal, such as that associated with food-seeking or wheel-running behavior. SPA is often thought of as only "fidgeting," but that is a mischaracterization, since fidgety behavior can be linked to stereotypies in neurodegenerative disease and other movement disorders. Instead, SPA should be thought of as all physical activity behavior that emanates from an unconscious drive for movement.RECENT FINDINGS: An example of this may be restless behavior, which can include fidgeting and gesticulating, frequent sit-to-stand movement, and more time spent standing and moving. All physical activity burns calories, and as such, SPA could be manipulated as a means to burn calories, and defend against weight gain and reduce excess adiposity. In this review, we discuss human and animal literature on the use of SPA in reducing weight gain, the neuromodulators that could be targeted to this end, and future directions in this field.
AB - PURPOSE OF REVIEW: Spontaneous physical activity (SPA) is a physical activity not motivated by a rewarding goal, such as that associated with food-seeking or wheel-running behavior. SPA is often thought of as only "fidgeting," but that is a mischaracterization, since fidgety behavior can be linked to stereotypies in neurodegenerative disease and other movement disorders. Instead, SPA should be thought of as all physical activity behavior that emanates from an unconscious drive for movement.RECENT FINDINGS: An example of this may be restless behavior, which can include fidgeting and gesticulating, frequent sit-to-stand movement, and more time spent standing and moving. All physical activity burns calories, and as such, SPA could be manipulated as a means to burn calories, and defend against weight gain and reduce excess adiposity. In this review, we discuss human and animal literature on the use of SPA in reducing weight gain, the neuromodulators that could be targeted to this end, and future directions in this field.
KW - Animal
KW - Brain
KW - Central nervous system
KW - DREADD
KW - Dynorphin
KW - Eating behavior
KW - Exercise
KW - Food intake
KW - Human
KW - Locomotion
KW - Non-exercise energy expenditure
KW - Obesity
KW - Optogenetics
KW - Orexin
KW - Spontaneous physical activity
UR - http://www.scopus.com/inward/record.url?scp=85049899976&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85049899976&partnerID=8YFLogxK
U2 - 10.1007/s13679-017-0288-1
DO - 10.1007/s13679-017-0288-1
M3 - Review article
C2 - 29101738
AN - SCOPUS:85049899976
SN - 2162-4968
VL - 6
SP - 362
EP - 370
JO - Current obesity reports
JF - Current obesity reports
IS - 4
ER -
