Standard Operating Procedures (SOPs) for Evaluating the Heart in Preclinical Studies of Duchenne Muscular Dystrophy

Dongsheng Duan, Jill A. Rafael-Fortney, Alison Blain, David A. Kass, Elizabeth M. McNally, Joseph M. Metzger, Christopher F. Spurney, Kathi Kinnett

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A recent working group meeting focused on contemporary cardiac issues in Duchenne muscular dystrophy (DMD) was hosted by the National Heart, Lung, and Blood Institute in collaboration with the Parent Project Muscular Dystrophy. An outcome of this meeting was to provide freely available detailed protocols for preclinical animal studies. The goal of these protocols is to improve the quality and reproducibility of cardiac preclinical studies aimed at developing new therapeutics for the prevention and treatment of DMD cardiomyopathy.

Original languageEnglish (US)
Pages (from-to)85-86
Number of pages2
JournalJournal of cardiovascular translational research
Volume9
Issue number1
DOIs
StatePublished - Feb 1 2016

Bibliographical note

Funding Information:
D.D. is a member of the scientific advisory board for Solid GT, a subsidiary of Solid Biosciences. The Duan lab received research support from Solid Biosciences in 2014 and 2015. The other authors report no conflicts.

Publisher Copyright:
© 2016, Springer Science+Business Media New York.

Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.

Keywords

  • Cardiology
  • Cardiomyopathy
  • Duchenne
  • Preclinical
  • Standard operating procedures (SOPs)

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