Sterol dynamics following portacaval shunt

John J. Coyle; Ignacio J. Guzman; Russell Hanson; Richard L. Varco; Henry Buchwald

doi:10.1016/0022-4804(77)90155-X

Sterol dynamics following portacaval shunt

John J. Coyle, Ignacio J. Guzman, Russell Hanson, Richard L. Varco, Henry Buchwald

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Abstract

This study reports lipid studies on dogs up to 44 weeks following portacaval shunt. We have shown portacaval shunt to be associated with significant decreases in plasma cholesterol and triglyceride levels in the dog. Cholesterol synthesis and absorption appear to be unchanged following operation when compared to control animals. Two-hour postprandial serum bile acids are fortyfold greater in shunted animals than in control dogs. Further studies of the interrelationship of bile acid and cholesterol metabolism following portacaval shunt are suggested.

Original language	English (US)
Pages (from-to)	348-351
Number of pages	4
Journal	Journal of Surgical Research
Volume	22
Issue number	4
DOIs	https://doi.org/10.1016/0022-4804(77)90155-X
State	Published - Apr 1977
Externally published	Yes

Bibliographical note

Funding Information:
1 Supported in part by grants from the National Heart and Lung Institute (HL 11901 and HL 15265).

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title = "Sterol dynamics following portacaval shunt",

abstract = "This study reports lipid studies on dogs up to 44 weeks following portacaval shunt. We have shown portacaval shunt to be associated with significant decreases in plasma cholesterol and triglyceride levels in the dog. Cholesterol synthesis and absorption appear to be unchanged following operation when compared to control animals. Two-hour postprandial serum bile acids are fortyfold greater in shunted animals than in control dogs. Further studies of the interrelationship of bile acid and cholesterol metabolism following portacaval shunt are suggested.",

author = "Coyle, {John J.} and Guzman, {Ignacio J.} and Russell Hanson and Varco, {Richard L.} and Henry Buchwald",

note = "Funding Information: 1 Supported in part by grants from the National Heart and Lung Institute (HL 11901 and HL 15265).",

year = "1977",

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doi = "10.1016/0022-4804(77)90155-X",

language = "English (US)",

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pages = "348--351",

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T1 - Sterol dynamics following portacaval shunt

AU - Coyle, John J.

AU - Guzman, Ignacio J.

AU - Hanson, Russell

AU - Varco, Richard L.

AU - Buchwald, Henry

N1 - Funding Information: 1 Supported in part by grants from the National Heart and Lung Institute (HL 11901 and HL 15265).

PY - 1977/4

Y1 - 1977/4

N2 - This study reports lipid studies on dogs up to 44 weeks following portacaval shunt. We have shown portacaval shunt to be associated with significant decreases in plasma cholesterol and triglyceride levels in the dog. Cholesterol synthesis and absorption appear to be unchanged following operation when compared to control animals. Two-hour postprandial serum bile acids are fortyfold greater in shunted animals than in control dogs. Further studies of the interrelationship of bile acid and cholesterol metabolism following portacaval shunt are suggested.

AB - This study reports lipid studies on dogs up to 44 weeks following portacaval shunt. We have shown portacaval shunt to be associated with significant decreases in plasma cholesterol and triglyceride levels in the dog. Cholesterol synthesis and absorption appear to be unchanged following operation when compared to control animals. Two-hour postprandial serum bile acids are fortyfold greater in shunted animals than in control dogs. Further studies of the interrelationship of bile acid and cholesterol metabolism following portacaval shunt are suggested.

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VL - 22

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JO - Journal of Surgical Research

JF - Journal of Surgical Research

IS - 4

ER -

Sterol dynamics following portacaval shunt

Abstract

Bibliographical note

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