Structural Characterization of the Major DNA-DNA Cross-Link of 1,2,3,4-Diepoxybutane

Chemical Compounds

• Covalent Structure 88%
• Nucleobase 65%
• Treosulfan 61%
• Guanine 58%
• Tumorigenic 44%
• Industrial Substance 40%
• Genotoxic 35%
• Alkylating Agent 35%
• Double-Stranded DNA 32%
• Prodrug 31%
• Carcinogenic 31%
• Reaction Half Life 28%
• Antitumor 27%
• Mass Spectrum 25%
• Alkylation 25%
• Mutation 25%
• Ultraviolet Spectrum 24%

Medicine & Life Sciences

• diepoxybutane 100%
• DNA 33%
• 1,3-butadiene 30%
• Guanine 23%
• 1,4-bis-(guan-7-yl)-2,3-butanediol 12%
• treosulfan 8%
• calf thymus DNA 7%
• Alkylation 6%
• Alkylating Agents 5%
• Laboratory Animals 5%
• Prodrugs 5%
• Point Mutation 4%
• Chromosome Aberrations 4%
• Half-Life 4%