Abstract
(+/-) Carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir) is an antiretroviral agent which is undergoing preclinical evaluation for the treatment of AIDS. Its hydrolytic stability and its ability to inhibit infectivity and replication of HIV in T-cells at concentrations of approximately 400-fold below toxic concentrations make Carbovir an excellent candidate for development as a potential antiretroviral agent.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 193-194 |
| Number of pages | 2 |
| Journal | Nucleic acids symposium series |
| Issue number | 25 |
| State | Published - 1991 |
