Targeted and Untargeted Detection of DNA Adducts of Aromatic Amine Carcinogens in Human Bladder by Ultra-Performance Liquid Chromatography-High-Resolution Mass Spectrometry

Medicine & Life Sciences

• DNA Adducts 100%
• Amines 84%
• 4-biphenylamine 82%
• Carcinogens 77%
• Mass Spectrometry 72%
• High Pressure Liquid Chromatography 66%
• Urinary Bladder 64%
• 2,6-xylidine 40%
• Urinary Bladder Neoplasms 38%
• Smoke 38%
• Tobacco 37%
• 2-toluidine 35%
• 2-Naphthylamine 34%
• N-(deoxyadenosin-8-yl)-4-aminobiphenyl 24%
• Meat 21%
• N-(deoxyguanosin-8-yl)-4-aminobiphenyl 21%
• 2-amino-9H-pyrido(2,3-b)indole 20%
• Formaldehyde 18%
• Paraffin 18%
• Lipid Peroxidation 18%
• 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline 17%
• Epidemiologic Studies 16%
• Nucleotides 16%
• 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine 15%
• calf thymus DNA 15%
• DNA 11%
• Limit of Detection 10%
• Occupational Exposure 10%
• Liquid Chromatography 10%
• Smokers 8%
• Ions 8%
• Carcinogenesis 7%

Chemical Compounds

• Aromatic Amine 82%
• Adduct 56%
• Mass Spectrometry 53%
• Liquid 43%
• Smoke 27%
• 2-Naphthylamine 19%
• 2-Amino-9H-pyrido[2,3-b]indole 10%
• Nucleotide 10%
• Lipid 8%
• Quinoxaline 6%
• Electrophile 6%
• Ionization 4%
• Pyridine 4%
• Ion 2%