TY - JOUR
T1 - Technical Aspects of Imaging and Transfemoral Arterial Treatment of N1-S1 Tumors in Rats
T2 - An Appropriate Model to Test the Biology and Therapeutic Response to Transarterial Treatments of Liver Cancers
AU - Ju, Shenghong
AU - McLennan, Gordon
AU - Bennett, Stacy L.
AU - Liang, Yun
AU - Bonnac, Laurent
AU - Pankiewicz, Krzysztof W.
AU - Jayaram, Hiremagalur N.
PY - 2009/3
Y1 - 2009/3
N2 - The present study was undertaken to assess the technical feasibility of transfemoral hepatic artery catheterization in rats and to describe the imaging techniques that can be used on tumors in rats. A total of 106 N1-S1 cells were inoculated into the left lobes of 74 rats. In 17, transfemoral angiography was attempted. Tumor volumes for 2 weeks before angiography were measured with magnetic resonance imaging in 40 animals. Tumors grew in 63 animals. Angiography was successful in 16 rats. Mean tumor volumes were 0.13 mL and 0.9 mL after 1 and 2 weeks, respectively. In conclusion, transfemoral hepatic artery catheterization is feasible in this animal model.
AB - The present study was undertaken to assess the technical feasibility of transfemoral hepatic artery catheterization in rats and to describe the imaging techniques that can be used on tumors in rats. A total of 106 N1-S1 cells were inoculated into the left lobes of 74 rats. In 17, transfemoral angiography was attempted. Tumor volumes for 2 weeks before angiography were measured with magnetic resonance imaging in 40 animals. Tumors grew in 63 animals. Angiography was successful in 16 rats. Mean tumor volumes were 0.13 mL and 0.9 mL after 1 and 2 weeks, respectively. In conclusion, transfemoral hepatic artery catheterization is feasible in this animal model.
UR - http://www.scopus.com/inward/record.url?scp=60649091879&partnerID=8YFLogxK
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U2 - 10.1016/j.jvir.2008.12.408
DO - 10.1016/j.jvir.2008.12.408
M3 - Article
C2 - 19167243
AN - SCOPUS:60649091879
SN - 1051-0443
VL - 20
SP - 410
EP - 414
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
IS - 3
ER -
