Objective: To establish baseline data for the Cardio Vision 2020 program, a collaborative project in Olmsted County, Minnesota, organized to reduce cardiovascular disease rates by altering 5 health-related items: (1) eliminating tobacco use and exposure, (2) improving nutrition, (3) increasing physical activity, (4) lowering serum cholesterol level, and (5) controlling blood pressure. Subjects and Methods: Data about tobacco use, diet, and physical activity were collected by random digit dial interview and follow-up questionnaire from a sample of the population. Blood pressure data were collected from medical records at Mayo Clinic, and serum cholesterol data were derived from the Mayo Clinic laboratory database. Data were stratified into 6 age groups. Results: A total of 624 women and 608 men responded to the questionnaire. Population blood pressure data were available for 1956 women and 1084 men. Population serum cholesterol data were available for 17,042 women and 12,511 men. Except for women in the 30- to 39-year-old age group, less than 10% of the population sampled met 4 or 5 goals. Conversely, about 90 % of the population met at least 1 goal, and about 80% met 1, 2, or 3 of the goals. Conclusion: The data from the Olmsted County population indicate considerable opportunity to reduce this population's burden of cardiovascular disease.