The chemistry of tryptanthrin and its derivatives

Ashli M. Tucker, Peter Grundt

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations

Abstract

Tryptanthrin (indolo[2,1-b]quinazoline-6,12-dione) is a natural product which shows significant biological activity as an antibacterial, antiparasitic, and antineoplastic agent. Historically, tryptanthrin has been found as a component of many dyes as well as a constituent of medicinal herbal treatments. This review describes the synthesis of tryptanthrin and some related compounds which also have a quinazoline ring fused to an indolo moiety as a core.

Original languageEnglish (US)
Pages (from-to)546-569
Number of pages24
JournalArkivoc
Volume2012
Issue number1
DOIs
StatePublished - Jul 29 2012

Keywords

  • Alkaloids
  • Indoles fused
  • Quinazolines fused
  • Tryptanthrin

Fingerprint Dive into the research topics of 'The chemistry of tryptanthrin and its derivatives'. Together they form a unique fingerprint.

Cite this