Maintaining energy homeostasis is critical for ensuring proper growth and maximizing survival potential of all organisms. Here we review the role of somatic muscle in regulating energy homeostasis in insects. The muscle is not only a large consumer of energy, it also plays a crucial role in regulating metabolic signaling pathways and energy stores of the organism. We examine the metabolic pathways required to supply the muscle with energy, as well as muscle-derived signals that regulate metabolic energy homeostasis.
Bibliographical noteFunding Information:
This work was supported by a grant from the National Institutes of Health grant 1R35GM118029 to MO’C and an IRACDA fellowship from NIH supported training grant K12 GM119955 to HB.