The use of a series of ketamine infusions in two patients with treatment-resistant depression

Michael Messer, Irina V. Haller, Pamela Larson, Julia Pattison-Crisostomo, Charles E. Gessert

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

Treatment-resistant depression often leads to increased morbidity and disability. The authors report the use of ketamine, a selective N-methyl-d-aspartate (NMDA) receptor antagonist, in two patients with treatment-resistant depression. Multiple ketamine treatments may provide an effective rapid antidepressant effect with prolonged benefit.

Original languageEnglish (US)
Pages (from-to)442-444
Number of pages3
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume22
Issue number4
DOIs
StatePublished - Jan 1 2010

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