Thermodynamic and structural basis of phosphorylation-induced disorder-to-order transition in the regulatory light chain of smooth muscle myosin

Medicine & Life Sciences

• Smooth Muscle Myosins 89%
• Thermodynamics 75%
• Light 44%
• Phosphorylation 43%
• Entropy 16%
• Periodicity 15%
• poly(tetramethylene succinate-co-tetramethylene adipate) 12%
• Static Electricity 8%
• Molecular Dynamics Simulation 7%
• Salts 6%
• Water 4%
• Peptides 4%
• Mutation 3%

Engineering & Materials Science

• Phosphorylation 100%
• Muscle 57%
• Thermodynamics 53%
• Entropy 11%
• Coulomb interactions 10%
• Peptides 9%
• Free energy 8%
• Molecular dynamics 7%
• Enthalpy 7%
• Salts 6%
• Computer simulation 3%
• Water 3%

Chemical Compounds

• Thermodynamics 38%
• Simulation 11%
• Mutation 7%
• Entropy 7%
• Gibbs Free Energy 6%
• Molecular Dynamics 6%
• Peptide 5%
• Energy 4%