We must critically rethink race and genetics in the context of the new genetic breakthroughs and haplotype mapping. We must avoid the slippery slope of turning socially constructed racial categories into genetic realities. It is a potentially dangerous arena given the history of racialized science in the United States and globally. Indeed, the new advances must be viewed in the context of a long history of racial inequality, continuing into the current period. Tills is more than a question of how carefully we use categories of analysis such as race. Justice and equity must be core to our considerations. There is a community stake in tills work that must be seriously considered and included in decision making. A progressive and critical analysis is in order.