Abstract
After a five-day adaptation period in activity wheels, four prairie dogs were assigned to a methylphenidate group (2.5 mg/kg, s.c.) and four prairie dogs were assigned to a saline group for ten consecutive daily injections. Half-revolutions of locomotor activity were recorded during seven measurement periods taken daily. During the third measurement period, from 1-3 hrs following injection, the methylphenidate group declined in locomotor activity over the first three days of drug administration.
Original language | English (US) |
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Pages (from-to) | 111-113 |
Number of pages | 3 |
Journal | Psychopharmacologia |
Volume | 46 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1976 |
Externally published | Yes |
Keywords
- Methylphenidate
- Motor activity
- Prairie dogs
- Tolerance