Transient autoimmune neutropenia due to anti-na1 antibody

John R. Priest, Mary E. Clay, Jeffrey McCullough, Norma K.C. Ramsay, Parviz Lalezari, William Krivit

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

A 6-month-old girl developed severe, but transient neutropenia due to an antibody against a neutrophil-specific antigen, NA1. The mean absolute neutrophil count was 380/μ1 for 2 months and spontaneously returned to normal as the anti-NAl antibody disappeared. After recovery, the NA1 antigen was demonstrated on the patient's neutrophils. No etiology was found. There was no therapy directed at suppressing the antibody or increasing the neutrophil count. Life-threatening infection did not occur during the neutropenia.

Original languageEnglish (US)
Pages (from-to)195-199
Number of pages5
JournalAmerican Journal of Pediatric Hematology/Oncology
Volume2
Issue number3
StatePublished - 1980

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