Urea small molecule agonists on mouse melanocortin receptors

Christine G. Joseph; Rayna M. Bauzo; Zhimin Xiang; Carrie Haskell-Luevano

doi:10.1016/S0960-894X(03)00318-4

Urea small molecule agonists on mouse melanocortin receptors

Christine G. Joseph, Rayna M. Bauzo, Zhimin Xiang, Carrie Haskell-Luevano

Medicinal Chemistry

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A series of urea compounds based on the tripeptide Phe-Trp-Lys were synthesized and pharmacologically characterized at the mouse melanocortin receptors. The results include identification of novel melanocortin receptor agonists with potencies ranging from nanomolar to micromolar.

Original language	English (US)
Pages (from-to)	2079-2082
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	13
Issue number	12
DOIs	https://doi.org/10.1016/S0960-894X(03)00318-4
State	Published - Jun 16 2003

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title = "Urea small molecule agonists on mouse melanocortin receptors",

abstract = "A series of urea compounds based on the tripeptide Phe-Trp-Lys were synthesized and pharmacologically characterized at the mouse melanocortin receptors. The results include identification of novel melanocortin receptor agonists with potencies ranging from nanomolar to micromolar.",

author = "Joseph, {Christine G.} and Bauzo, {Rayna M.} and Zhimin Xiang and Carrie Haskell-Luevano",

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AU - Bauzo, Rayna M.

AU - Xiang, Zhimin

AU - Haskell-Luevano, Carrie

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N2 - A series of urea compounds based on the tripeptide Phe-Trp-Lys were synthesized and pharmacologically characterized at the mouse melanocortin receptors. The results include identification of novel melanocortin receptor agonists with potencies ranging from nanomolar to micromolar.

AB - A series of urea compounds based on the tripeptide Phe-Trp-Lys were synthesized and pharmacologically characterized at the mouse melanocortin receptors. The results include identification of novel melanocortin receptor agonists with potencies ranging from nanomolar to micromolar.

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