Vertebral osteomyelitis with profound neurologic deficit: Successful treatment with rhBMP-2 and titanium cage device

Research output: Contribution to journalArticlepeer-review

Abstract

The efficacy of bone morphogenetic proteins (BMP) in infection has not yet been established. Since fusion is a necessary aim in the treatment of vertebral osteomyelitis with spinal instability, BMP may be a helpful adjunct in the surgical treatment of these cases. We present a case of vertebral osteomyelitis associated with neurologic deficits, treated with decompression and fusion using recombinant human bone morphogenetic protein-2 (rhBMP-2) and titanium cage device. Eradication of infection, recovery of neurologic deficits, spinal stabilization and solid fusion were achieved and maintained at 5 years follow-up.

Original languageEnglish (US)
Pages (from-to)69-73
Number of pages5
JournalActa Medica Philippina
Volume46
Issue number2
StatePublished - Sep 27 2012

Keywords

  • Bone morphogenetic proteins
  • RhBMP-2
  • Titanium cage
  • Vertebral osteomyelitis

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