Zebrafish z-otu, a novel Otu and Tudor domain-containing gene, is expressed in early stages of oogenesis and embryogenesis

Saijun Mo, Ping Song, Daoyuan Lv, Yungui Chen, Wei Zhou, Wuming Gong, Zuoyan Zhu

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Several studies have suggested that Otu domain had de-ubiquitinating activity and Tudor domain was important for the formation of germ cells. Here, we reported a novel zebrafish ovary-specific gene containing Otu and Tudor domain, z-otu, which was expressed at stages I-III oocytes and embryonic stages from zygotes to early blastula during embryonic cells maintained their totipotency. Therefore, z-otu might link the ubiquitin signaling pathway to early oogenesis and maintaining the totipotency of embryonic cell.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalBiochimica et Biophysica Acta - Gene Structure and Expression
Volume1732
Issue number1-3
DOIs
StatePublished - Dec 30 2005

Bibliographical note

Funding Information:
This work was supported by grants from the ICGEB (International Center for Genetic Engineering and Biotechnology) (CRP/CHN02-01), the National Basic Research Program of China (No. 2004CB117400), and the National Natural Science Foundation of China (No. 30150005; No. 30270675).

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

Keywords

  • Embryogenesis
  • Oogenesis
  • Otu domain
  • Tudor domain
  • Z-otu
  • Zebrafish

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